Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, ...

Chemokines, acting as "traffic controllers" in the tumor microenvironment, regulate immune cell infiltration and local ...

Macrophages, key regulators of tissue health and immune defense, are among the most abundant immune cells in solid tumors. Their role in cancer has been difficult to define because even closely ...

Cancer immunology is advancing rapidly as researchers seek to unravel the complex, dynamic relationships between tumor cells, immune populations, and the ...

A study demonstrates that levels of the CTHRC1 protein in tumor-associated fibroblasts can predict immunotherapy outcomes in ...

Determining the presence of a protein in non-tumor cells within the cancer microenvironment could be one of the keys to ...

Current research investigates novel biomarkers that can predict therapeutic outcomes. Finding ways to determine therapeutic ...

A new drug that works by making tumors more susceptible to chemotherapy and the immune system has increased survival in those ...

Dyve Biosciences, in collaboration with Moffitt Cancer Center, today reported significant study results for a first-of-its-kind investigational therapy applied to the skin and des ...

Triple-negative breast cancer (TNBC), particularly the luminal androgen receptor (LAR) subtype, presents significant ...

Translational study in metastatic triple-negative breast cancer (mTNBC) shows leronlimab-mediated CCR5 inhibition induces PD-L1 expression, ...